3.7 Risk Assessment (2/3) Copy

• Previous stillbirth is considered an increased risk, regardless of size and stated cause, unless placental insufficiency has been reliably excluded by placental pathology examination.
• For women with a history of, or significant risk factor for, placental dysfunction (including history of pre-eclampsia or fetal growth restriction), Aspirin 75-150mg nocte is recommended from 12 weeks to birth according to latest NICE guidelines ^20,38

20.  Rolnik DL, Wright D, Poon LCY, Syngelaki A, O’Gorman N, Matallana C de P, et al. ASPRE trial: performance of screening for preterm pre-eclampsia. Ultrasound in Obstetrics & Gynecology. 2017;50(4):492–5. https://doi.org/10.1002/uog.18816

38. National Institute for Health and Care Excellence. Hypertension in pregnancy: diagnosis and management (Clinical Guideline 133). NICE 2019  www.nice.org.uk/guidance/ng133